منابع مشابه
Commemorative Lecture
In the neurogenic niche of the adult mammalian brain, self-renewing neural stem cells (NSCs) give rise to committed neuronal progenitors within the subgranular zone (SGZ) of the dentate gyrus (DG).1 Astrocytes are an essential cell population that defines the SGZ niche, and astrocyte-derived factors have instructive effects that promote adult neurogenesis.2, 3 Recently, we showed that Wnt3 expr...
متن کاملCommemorative Lecture
The ob gene was cloned in 1994 using the methodology of positional cloning. Leptin, the protein encoded by the ob gene, was identified in 1995 and shown to be a hormonal signal that regulates energy balance.14 Since its discovery 15 years ago, 30,943 articles on leptin have been written (S Korres, personal communication, 2009), providing an opportunity to assess, with some hindsight, the impact...
متن کاملCOMMEMORATIVE LECTURE Neural mechanisms of cognitive memory
It is my great honor to be here for the award of the 2003 Keio Medical Science Prize. I express my gratitude to Keio University and Dr. Mitsunada Sakaguchi. Knowledge or experiences are voluntarily recalled from memory by reactivation of their neural representations in the cerebral association cortex. Four questions are central in understanding this process: (1) Where in the brain is the mnemon...
متن کاملOnderstepoort today, yesterday and tomorrow. Commemorative lecture.
This lecture commences with a synopsis of the present activities and organization of the world-famous veterinary research institute in South Africa, colloquially and internationally known as Onderstepoort. Some of the major historic features which contributed to the origin, firm establishment and excellent reputation of Onderstepoort are subsequently outlined. Finally, the future of the institu...
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ژورنال
عنوان ژورنال: British Dental Journal
سال: 2013
ISSN: 0007-0610,1476-5373
DOI: 10.1038/sj.bdj.2013.873